The two, who were not identified, were found by US Border Patrol agents on Thursday, with their attention affixed to their phones as they were trying to hunt down cartoon characters on a journey that took them over the border.
(Also see: How to Download Pokemon Go APK, Install, and Play on Android)
"Both juveniles were so captivated by their Pokemon Go games that they lost track of where they were," said Michael Rappold, a spokesman for the agency.
(Also see: Pokemon Go iOS: How to Download Pokemon Go for iPhone, iPad)
The two were reunited with their mothers at a nearby border patrol station, the agency said.
The game has been an unexpected success from Spain to Australia, doubling Nintendo's value since the game's launch in the United States earlier this month.
Using mobile devices, players search for virtual Pokemon characters that appear to pop up at office spaces, restaurants, museums and other places. Players score points in various ways, including capturing the Pokemon characters with a flick of a finger on their phone screen.
The game was also to blame for a rash of car accidents and a slew of mishaps stemming from distracted players.
© Thomson Reuters 2016
For the latest tech news and reviews, follow Gadgets 360 on X, Facebook, WhatsApp, Threads and Google News. For the latest videos on gadgets and tech, subscribe to our YouTube channel. If you want to know everything about top influencers, follow our in-house Who'sThat360 on Instagram and YouTube.